Formulation and characterization of liposomal encapsulated systems of bioactive ingredients from traditional plant mountain germander (Teucrium montanum L.) for the incorporation into coffee drinks.
Retention prediction of monoamine neurotransmitters in gradient liquid chromatography. Jiří Urban, Martina Nechvátalová, Lukáš Hekerle.Direct Infusion-Three-Dimensional-Mass Spectrometry Enables Rapid Chemome Comparison among Herbal Medicines. Xia Xu, Wei Li, Ting Li, Ke Zhang, Qingqing Song, Li Liu, Pengfei Tu, Yitao Wang, Yuelin Song, Jun Li.Journal of Agricultural and Food Chemistry 2020, 68 Confirmative Structural Annotation for Metabolites of (R)-7,3′-Dihydroxy-4′-methoxy-8-methylflavane, A Natural Sweet Taste Modulator, by Liquid Chromatography–Three-Dimensional Mass Spectrometry. Guan Pengwei, Qingqing Song, Ting Li, Libo Cao, Huiting Tang, Yitao Wang, Pengfei Tu, Jiao Zheng, Yuelin Song, Jun Li.Prediction of Analyte Retention Time in Liquid Chromatography. Integrated Strategy Drives Direct Infusion–Tandem Mass Spectrometry as an Eligible Tool for Shotgun Pseudo-Targeted Metabolomics of Medicinal Plants. Ke Zhang, Wenjing Liu, Qingqing Song, Jian-Bo Wan, Juan Yu, Xingcheng Gong, Libo Cao, Dandan Si, Pengfei Tu, Jun Li, Yuelin Song.
#NAMELY TIME FULL#
Full Collision Energy Ramp-MS2 Spectrum in Structural Analysis Relying on MS/MS. Pengwei Guan, Wenjing Liu, Yan Cao, Huiting Tang, Huixia Huo, Jian-Bo Wan, Xue Qiao, Pengfei Tu, Jun Li, Yuelin Song.This article is cited by 26 publications. Above all, the integration of retention and dissociation behaviors enabled promoting one step forward for structural annotation confidences merely relied on HR-MS/MS. Structural identification was validated by oral administration of three relevant compounds in parallel and chromatographic purification as well. Nineteen metabolites ( M1– M19) were confidently identified in biological samples from echinacoside-treated rats by analyzing m/ z values first to yield empirical formulas and substructures, and t R and OCE subsequently contributed to sift the candidate structures. Online energy-resolved MS was developed to yield breakdown graphs for selected ion transitions, and OCE was demonstrated to be superior to CE 50 toward pointedly denoting the bonds-of-interest. Quantitative structure-retention relationships (QSRR) were modeled via assaying 184 authentic compounds on RPLC, HILIC, and serially coupled RPLC and HILIC (RPLC-HILIC). Herein, we made an attempt to involve retention time ( t R) along with optimal collision energy (OCE) as the additionally structural clues, and the applicability validation was conducted via confidence-enhanced metabolite characterization of echinacoside, an antidementia drug candidate within clinical trials. More auxiliary evidence is therefore desired to achieve confirmative identification. The structural annotation of metabolites now relies heavily on HR-MS/MS information, resulting in ambiguous identities in most cases.
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